OUTSMARTING TROGOCYTOSIS TO BOOST CAR NK/T CELL THERAPY

Outsmarting trogocytosis to boost CAR NK/T cell therapy

Abstract Chimeric antigen receptor (CAR) NK and T cell therapy are promising immunotherapeutic approaches for the treatment of cancer.However, the efficacy of CAR NK/T cell therapy is often hindered by various factors, including the phenomenon of school bus trogocytosis, which involves the bidirectional exchange of membrane fragments between cells.

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Species delimitation in asexual insects of economic importance: The case of black scale (Parasaissetia nigra), a cosmopolitan parthenogenetic pest scale insect.

Asexual lineages provide a challenge to species delimitation because species concepts either have little biological meaning for them or are arbitrary, since every individual is monophyletic and reproductively isolated from all other individuals.However, recognition and naming of asexual species is important to conservation and Hall Tree economic ap

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